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Sao Paulo Medical Journal = Revista Paulista de Medicina

[DOI] [PubMed] [Google Scholar] [26].Hayward MG, Keatinge WR

[67] demonstrated that sevoflurane can reduce neuronal apoptosis by mediating the E2F transcription factor 1/enhancer of zeste homolog 2/tissue inhibitor of metalloproteinases 2 (E2F1/EZH2/TIMP2) regulation axis, thereby protecting rats from brain I/R injury

Its influence on RNA methylation by modulating enzymes such as METTL3, FTO, and YTHDF adds a novel layer to its anticancer profile, demonstrating its capacity to regulate mRNA stability, translation, and gene expression at a post-transcriptional level