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This cascade is consistent with an inflammation-stress two-hit model (Espinosa-Garcia et al., 2021)

The strategy established here may enable more rational dose translation, streamline early screening of nanoformulations, and ultimately contribute to the progression of NC-CUR toward advanced preclinical and future clinical development

To further evaluate the binding of phage clones expressing the lead peptide sequences CTVRTSAEC, CIGNSNTLC and DWSSWVYRDPQT to SKOV3 cells in vitro, homogenous phage solutions were incubated on SKOV3 cells, and their binding detected using and anti-M13 antibody

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Riociguat for the treatment of pulmonary arterial hypertension associated with connective tissue disease: results from PATENT-1 and PATENT-2