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Common Deficiency Symptoms Common symptoms of Vitamin B12 deficiency include: Fatigue Weakness Pale skin Shortness Mouth Issues: Sore, red tongue, mouth ulcers, bleeding gums Gastrointestinal: Loss of appetite, weight loss, nausea, diarrhea, constipation Nerve issues like numbness/tingling Mood changes (depression, irritability) Memory problems Key Differences: NAD+ vs B12 NAD+ and B12 both boost energy, but NAD+ acts as a deep cellular, anti-aging repair agent, while B12 provides immediate metabolic energy and red blood cell support

Transdermal gels and creams (both FDA-approved and compounded), vaginal preparations for genitourinary symptoms, sublingual troches, and injectable estradiol are all available

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Conclusion: AOD 9604 significantly improves bone density and bone mass in elderly osteoporotic rats, while promoting bone formation and inhibiting bone resorption, with better effects than bisphosphonates that simply inhibit bone resorption

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