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Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development

doi: 10.1038/ncpendmet0424 38 ShahidMAAshrafMASharmaS

As a result, it causes immune-mediated enteropathy, intestinal inflammation, followed by the atrophy of villi, crypt hyperplasia and increased infiltration by intraepithelial lymphocytes [11]

JNK Signaling Pathway JNK signaling is a component of the mitogen-activated protein kinase (MAPK) signaling system, which is important in stress signaling pathways including gene expression, neural development, and cell survival