l carnitine good for lactic acid L-Carnitine | Linus Pauling Institute Liquid L-Carnitine - Citrus

PLoS ONE 7 , e42301 (2012)

Cyanocobalamin (vitamin B12)

Considering Konzo is an Afro-centric disease that affects very isolated communities, global collaborations are necessary to utilize the most advanced scientific technologies to conduct high-throughput measures as presented in this work

Nevertheless, to our knowledge, this is the only study to have assessed week-to-week variability in these blood parameters at baseline, thus it is unknown whether the variability is due to the technician, machine error, the assay, or from true biological variability

Notably, curcumin activates 5-adenosine monophosphate-activated protein kinase (AMPK) and inhibits mTOR (Zuo et al., 2021), remodels autophagy homeostasis to eliminate UV-induced damaged proteins, and regulates the Bcl-2/caspase-3 balance (Liu et al., 2018) and CD39/CD73-adenosine pathway (Manica et al., 2024), achieving a precise balance between anti-apoptosis and pro-repair