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Moreover, there is a risk of developing tolerance or dependence on weight loss pills, which may result in reduced efficacy over time or difficulty in maintaining weight loss once the medication is discontinued

Resistance training, adequate protein intake (1.2-1.6 g/kg/day, adjusted to actual body weight), and consideration of complementary compounds that support lean mass, such as tesamorelin for GH-mediated anabolic support or CJC-1295/Ipamorelin for broader GH optimization, become increasingly important with longer treatment duration

But first here are five signs your body might be asking for one

J Pediatr

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