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These studies have provided important clues to understand the mechanism of action of carnitine in different pathological states and laid the foundation for the development of new therapeutic strategies

Atenolol (does not cross the blood-brain barrier) had no effect on binge-like alcohol drinking ( p = 0.9848), whereas metoprolol (crosses the blood-brain barrier) decreased binge-like alcohol drinking compared with vehicle-treated mice ( p = 0.0096)

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