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Over the past decade, immunotherapya treatment that helps the patient's own immune system recognize and destroy cancer cellshas become an important option for some cancers, and adds to traditional approaches like chemotherapy, radiation, and surgery

Glucocorticoids, secreted primarily by the adrenal glands, are important clinical drugs used to control pain and reduce inflammation in autoimmune diseases, neurological injury, cancer, and more

the stem of the stemloop is extended by at least 1, 2, 3, 4, 5 or more complementary basepairs (i.e

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In some embodiments, this can be achieved by mRNA or protein modifications