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doi: 10.2217/nnm.12.176 426 LiuZXiongLOuyangGMaLSahiSWangKet al

Science 264:17721775 Ramesh T, Lyon AN, Pineda RH et al (2010) A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease

Doses above this threshold dont produce proportional increases in GH secretion due to receptor saturation and increased likelihood of desensitisation with chronic use