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The expression of myelin proteins MBP and MOG were assessed at 1- and 2- weeks post-treatment

Similarly, in human lung carcinoma A549 cells, mangiferin exhibits antineoplastic properties, by inducing G2/M phase cell cycle arrest via downregulation of the cyclin-dependent kinase 1-cyclin B1 signaling pathway and inducing apoptotic cell death by inhibiting the PKC-NF-B pathway (55)

Chemopreventive effects of curcumin on glandular stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine and sodium chloride in rats

Oxidative stress releases pro-inflammatory molecules that interact with ROS to produce inflammation, performing major role in early onset of aging and metabolic diseases [7]

J Nutr 134:20042010 Tang L, Zhang Y (2005) Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells