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The form and function of tissues is highly dependent on the ECM, a mesh-like network of molecules, including proteins (collagens, elastins), proteoglycans (glycosaminoglycans, heparan sulfate), and hyaluronic acid

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Xiaflex is the first (and currently only) FDA-approved treatment proven effective for Peyronie's disease in men with a palpable plaque and a curvature deformity of 30 degrees or greater at the start of the treatment

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