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Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss

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Patel et al., 2020

As one of the most studied copper peptides in the scientific literature, GHK-Cu skin research has been particularly prolific, with numerous published studies exploring its role in extracellular matrix biology, collagen synthesis, and tissue remodeling processes

Others include a self-micro emulsifying berberine-phospholipid complex of polyethylene glycol 1000 succinate (TPGS 1000) and SiO, phytosomes loaded with berberine-phospholipid complex, solid lipid nanoparticles, micelles, liposomes of various nature, etc