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Despite this, NMDA receptor antagonists are occasionally prescribed off-label for mild to moderate cases of AD, raising concerns about their effectiveness in such instances [31]

doi: 10.1093/TAS/TXZ026 35 CrouseM

Of the eight GPxs, GPx4 is essential for life as the mice lacking it (knock out or KO) do not survive [1, 8, 9]

Although an inflammatory phenotype was not detected in the brain, systemic immune dysregulation was suggested by significant decreases of IFN, TNF, IL-1, and IL10 (Zakirova et al., 2017)