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C., Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response

Each design rule is supported below by comparative evidence and representative primary studies (2831)

For these features, T1 was used as an adjuvant or immunotherapeutic agent to treat disparate human diseases, including viral infections, immunodeficiencies and malignancies (Romani et al., 2012)

Human clinical context: AOD-9604 progressed through Phase 2 trials

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