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Perilipin 1, a lipid droplet scaffold protein that coordinates interactions with ABHD5 and HSL Perilipin 1 (PLIN1), initially discovered by the group of Constantine Londos, is the major adipocyte perilipin/ADRP/TIP47 (PAT) protein (35) that functions as a scaffold to organized protein-protein interactions on the surface of LDs (36)

As obesity rates continue to soar globally, with approximately 13% of the worlds adult population classified as obese [1], the urgency to develop effective interventions has never been more pronounced

Patients considering lipotropic injections should be counselled that these products are not substitutes for evidence-based weight management strategies and may represent unnecessary expense without proven benefit