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65 This protection is achieved through a variety of biological processes, including interactions with transition metals, neutralization of free radicals, modification of the activity of different enzymes, and impacts on intracellular signaling pathways and gene expression

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Arch Toxicol 88:391401 McJunkin B, Barwick KW, Little WC, Winfield JB (1976) Fatal massive hepatic necrosis following acetaminophen overdose