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Indeed, UBX0101 treatment on aged mice with post-traumatic OA after surgery reduces the presence of senescent cells, improves articular cartilage, and upregulates the expression of genes involved in new cartilage growth 25

On the contrary, no inhibitory effects were observed for hits 1, 4, and 15, at least at the tested concentrations (Table 1), suggesting possible cell permeability issues for these compounds

There was a slight up-regulated green fluorescence signal in the ZFP groups compared to the Control and US groups, which could be attributed to the chemodynamic property of Fe ions released by ZFP NPs

Gut microbes in polycystic ovary syndrome and associated comorbidities

(2013) 2013:CD000993