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(4) in human HS, RBC pyruvate content of 4.2 / mice was unchanged, but the PK activity was increased, most likely due to the persistent expression of both PKr and PKm2 isoforms and the increased reticulocyte count

doi:10.1155/2017/1259510

By one month (II), these cells showed increased presence within the central regions of the graft, suggesting active participation in tissue remodeling