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The interaction between iron and -Syn appears to create a detrimental cycle, and interventions aimed at reducing iron accumulation may effectively mitigate -Syn buildup and spread

These peptides signal the body to perform various functions, such as promoting healing, regulating hormones, and enhancing metabolic processes

Bioorganic & Medicinal Chemistry , 103 , 117681

This review has highlighted the complexity and heterogeneity of NSCLC metabolism, revealing that tumors do not uniformly rely on a single metabolic pathway but rather exhibit plasticity, utilizing glycolysis, OXPHOS, glutaminolysis, fatty acid metabolism, and other pathways in context-dependent manners

Ultimately, within the EGFR-mutated NSCLCs TME, significant Treg inroad exists in the setting of the non-inflammatory TME