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Cancer and Metastasis Reviews , 11 (34), 227235

Signs of Vitamin B12 deficiency include: Fatigue Heart palpitations Pale skin Constipation Loss of appetite Mental fog Nerve problems Dr

doi:10.1093/fampra/cml008

References Anemia, Pernicious- Rare Disease Database, NORD, National Organization for Rare Disorders [Internet]

Hence, purification techniques are essential for the isolation of pure CQDs from other unwanted products to ensure purity, while also narrowing down overall size distribution