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Description

The combination treatment, at a non-myeloablative dose, that was maximum tolerated by beige-nude-xid mice induced CRs in 100% of the MM.1S and OPM-2 xenografts, while 25% of mice achieved a CR in KMS-12-PE xenografts

La sintesi endogena avviene a partire dal substrato TML (6-N-trimetillisina), che a sua volta deriva dalla metilazione dell'amminoacido lisina

Briefly, reads were quality controlled and assembled, after which genes were called from the contigs and annotated following the Joint Genome Institutes (JGI) guidelines 34