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thus, they can detoxify various harmful substances including reactive oxygen species (ROS) ( GSTP1 gene is located on chromosome 11 (11q13) ( GSTP1 genetic variants are the rs1695

doi: 10.1007/s12149-017-1169-0 54 CeddiaRCollinsS

Its important to remember that while dark spots are usually harmless, any changes in your skin should be evaluated by a healthcare provider to rule out serious conditions like skin cancer

They interfere with signal transduction in melanocytes, leading to the death of these cells and acting as a mediator of the damaging effects of oxidative stress [22]

doi: 10.1073/pnas.1507228112 157 NicklinPBergmanPZhangBTriantafellowEWangHNyfelerBet al