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A review published in Gynecological Endocrinology by Calleja-Agius and Brincat (2012) described a strong correlation between skin collagen loss and oestrogen deficiency, noting that oestrogen replacement after menopause increased collagen content, dermal thickness and elasticity (PMID: 21970508)

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Future studies utilizing conditional knockout models and endogenous tagging approaches will be valuable in further validating these findings

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Majumdar et al., 2016

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J Cell Biol 218(8):25832599 Chen Y, Azad MB, Gibson SB (2009) Superoxide is the major reactive oxygen species regulating autophagy

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