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H 2 O 2 detection The release of H 2 O 2 , a reactive oxygen species produced by iRPE cells, was detected via a bioluminescence assay via a ROS-Glo kit (Promega, Charbonnires-les-Bains, France) according to the manufacturers instructions

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Vilarinho, Yale School of Medicine, New Haven, CT Background: Chronic liver disease (CLD) is the 11 th leading cause of death worldwide

Glaucoma and myopia, for example, can be considered as mechanotransduction diseases that reflect the dysfunctional response of cells in the eye to specific types of local mechanical stress