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& Drucker, D.J

Zhu et al., 2020), the significantly enriched mucinophilic genus Akkermansia , a representative of the Verrucomicrobia phylum, was negatively associated with cardiovascular disease and inflammatory response

Under oxidative stress, ROS modifies occludins and claudins and causes the formation of disulfide bonds, impairing their ability in forming tight junctions and weakening the barrier (89)

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IgG26AW has high affinity, high neutralization ability and occupies a new binding epitope that binds both to IL-1RI and IL-1RAcP, which has been validated in tumors and may be a potential drug for RA in the future (Kuo et al., 2021)