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This method ensures rapid and complete absorption, making it the preferred choice for patients with absorption issues, such as those with pernicious anemia, gastrointestinal disorders (like Crohns disease or celiac disease), or those who have had gastric bypass surgery

Sigma-Aldrich, Germany) and mixed for another 90 min at 37C

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It lies between the blood and the vessel wall, is synthesized and secreted by vascular endothelial cells, and is a dynamic natural barrier that is principally composed of proteoglycans, membrane glycoproteins, and plasma proteins, of which proteoglycans and glycoproteins are the main components (16)

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