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Chronic kidney disease patients often demonstrate elevated B12 levels, particularly those on dialysis

Recognising symptoms is important to avoid further health complications

Many cases start here until the workup is complete

Inflammation eliminates and repairs damaged cells

Current models do not fully explain the mechanisms underlying resistance to therapy ( + MM cells within hours to days after the first infusion ( Figure 6 ), underscore the need to further investigation into the CD38/ADA/purinergic axis to optimize anti-CD38 strategies in MM