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We concluded that the minimal binding region of CEP192 is aa 468533, based on the NMR and HDX-MS studies

Informed consent statement All adult patients or the parents of each child provided written informed consent after illustrating the purpose and the nature of the study to anonymous data collection and analysis for research purposes

Detection of mitochondrial membrane potential Cells were stained with 10 nM MitoTracker Deep Red (MDR, M22426, ThermoFisher) and 100 nM MitoTracker Green (MG, M46750, ThermoFisher) separately at 37 for 15 min to measure mitochondrial membrane potential and total mass

It is free from genetically modified organisms (GMOs), suitable for vegans, and does not contain gluten, making it a versatile and inclusive choice

The difference between 5 units and 7 units on a syringe is tiny, and that small measurement error could mean a 40% dosing difference