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Both compounds are evaluated for their interaction with intracellular signaling networks and peptide-mediated communication pathways

Depletion of GSH due to intensified oxidative stress or the action of inhibitors significantly reduces the ability of GPX4 to counteract lipid peroxidation, leading to increased lipid peroxides and subsequent ferroptosis (151)

Discovery of mitophagy inhibitors with therapeutic potential in different familial amyotrophic lateral sclerosis mutations