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Additionally, niacin has been noted to increase fasting blood glucose by inducing insulin resistance in some cases

Jacobson A, Lam L, Rajendram M, Tamburini F, Honeycutt J, Pham T, et al

Human-equivalent-dose extrapolation from that protocol lands around 650 mg/day for an 80 kg adult, but no human has been studied at any dose in a published trial