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Acknowledgements The authors would like to express their gratitude to Margreet Osinga (Gelderse Vallei Hospital, Ede, the Netherlands), Annelies Botman (Spaarne Gasthuis, Haarlem, the Netherlands), Fellery de Lange (Medical Center Leeuwarden, Leeuwarden, the Netherlands), Jantine van Holten (Ikazia Hospital, Rotterdam, the Netherlands), Jankees K.H

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By contrast, the International Lyme and Associated Diseases Society (ILADS) have issued markedly different clinical recommendations focused on often open-ended antibiotic treatment of persistent infection and the potential for multiple tick-borne co-infecting agents (162)