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Cystinosin deficiency leads to impaired lysosomal clearance and disrupted endolysosomal trafficking, which in turn contributes to defective autophagy and altered proteostasis [144, 146, 147]

Certain rumen microbes have been associated with the accumulation of AAs deposition of AAs and lipid metabolites in muscle tissue (Wang et al., 2021)

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References [1] Fasano A