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doi: 10.1016/j.mce.2016.11.003

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7.1 Isolation techniques Isolation approaches differ in terms of their capacity to distinguish soluble elements from EXOs and the dimensions of the EXOs they can isolate (Le Gall et al., 2020)

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Thus, epimutants exhibit variegation where the ratio of high ROS/insult-resistant to low ROS/insult-sensitive cells fluctuates in a cell population, and different states can be selected depending on the growth environment