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Roldan, A

This precise transcriptional regulation strategy effectively reversed the senescent phenotype of endothelial cells and inhibited pro-atherosclerotic EndoMT (Pernomian et al., 2024)

Kurokawa et al., 2014a, b)

Dual targeting of serine availability, through PHGDH inhibition and dietary restriction, represents a promising therapeutic paradigm to overcome resistance in this aggressive subtype