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we observed a strong growth defect and massive cell death in the LHON-edited cells, but not in the SILENT-edited cells (population doublings per day: LHON 0.64 0.11, SILENT 0.52 0.07

Only articles written in the English language were considered

Doering, Faculty of Health Sciences, Department of Pathology and Molecular Medicine, McMaster University, HSC 1R1, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada e-mail: [email protected] This article was submitted to the journal Frontiers in Cellular Neuroscience