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This artificial sweetener-induced glucose intolerance was mediated by changes to the commensal microbiota, with contributions from diverse bacterial taxa, because treatment with broad spectrum antibiotics protected animals against glucose intolerance phenotype

doi: 10.1161/CIRCULATIONAHA.110.958033 40 HuT.ShiJ

72 , 248254 (1976) Geraldine, P

PEG hydrogels are employed as polymeric carriers for carrier-linked prodrugs, it is desirable to deplete the hydrogel of its drug load before disintegration of the hydrogel material takes place

As noted by Kraus et al., Nature Medicine , NNMT inhibition in white adipose tissue significantly increased energy expenditure and reduced fat mass in animal models without changes to diet or activity