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Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics

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This decline has led some researchers to speculate that reduced GHK signaling could contribute to age-related impairments in: wound healing tissue repair collagen production While this hypothesis remains under investigation, it helps explain why GHK-Cu supplementationparticularly through topical formulationshas become a focus of dermatologic research