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Besides, both depressive and manic subgroups were characterized by presenting low levels of KYNA in comparison to healthy controls, which seems to support the relevance of the Kyn pathway in the context of neuroinflammation in BD and how it may be differentially modulated

In rodents, the SCN is composed of approximately 20,000 neurons, each functioning as an autonomous oscillator (Wang et al., 2015

Toomey R, Kang HK, Karlinsky J, Baker DG, Vasterling JJ, Alpern R et al (2007) Mental health of US Gulf War veterans 10 years after the war

FSP1-CoQ10 pathway Ferroptosis suppressor protein 1 (FSP-1, also known as flavoprotein apoptosis-inducing factor mitochondria-associated 2, AIFM2) has been identified as a glutathione-independent ferroptosis inhibitor [60]

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