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[8] [15] Mammalian cytosolic GSTs are dimeric, with both subunits being from the same class of GSTs, although not necessarily identical

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5 There is increased aromatase, which produces estrogen, as well as decreased 17-hydroxysteroid dehydrogenase 2 (17-HSD2), which breaks down estradiol to estrone, a more inert form of estrogen

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As a compensatory mechanism, the thyroid will enlarge to counteract the reduced hormone production

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2 h) induces Bax translocation and cytochrome c release via inhibition of Bcl-2 and Bcl-xL in H146 cells

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