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Identification of a mutation that relieves gamma-glutamyl kinase from allosteric feedback inhibition by proline

Molecular dynamics and structure-activity relationships identify molecular determinants of isoxazole 1 inhibition of Cn Acs1 To further characterize the interactions that contribute to the binding of isoxazole 1 to Cn Acs1, we performed molecular dynamics (MD) simulations using Schrdinger software as described in the Methods and Table S4

[DOI] [PubMed] [Google Scholar] 84.Alkhalaf A., Kleefstra N., Groenier K.H., Bilo H.J., Gans R.O., Heeringa P., et al

Nevertheless, supplementation with 2 mg/d folic acid, 25 mg/d vitamin B6, and 400 g/d B12 during 6 months significantly decreased the homocysteine levels, severity, and disability of migraine attacks (60)

Tracheal regeneration: evidence of bone marrow mesenchymal stem cell involvement