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Having an excess of vitamin D can lower vitamin K levels, which makes it more difficult for your body to use calcium properly, leading to brittle bones, bone loss, and bone pain

J.MacKayG.NixonC.et al (2017)

However, maintaining B12 status during aggressive weight loss prevents the potential complication of developing new deficiencies while correcting obesity-related metabolic dysfunction

Metabolomic profiling supported these transcriptomic and epigenomic changes, revealing altered levels of several metabolites associated with AKT1-driven pathways, including arginine, NADP, glycerol, guanosine, and glutamate

A.CisnerosJ.Toscano-MarquezF.et al (2019)