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Ultrastructural characteristics of the skin in a form of the EhlersDanlos syndrome type IV

An increase in ROS accumulation and a decrease in enzymatic (superoxide dismutase and catalase) and non-enzymatic defenses (reduced glutathione levels) were also observed, leading to oxidative stress and consequent oxidative injury: lipid peroxidation and loss of cell membrane integrity (Machado and Soares 2021b)

Rheumatoid Arthritis (RA): Rheumatoid arthritis symptoms can temporarily improve during pregnancy (due to high estrogen), but worsen again after menopause