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Translation of sulfide-based therapy to clinical practice has been stymied due to the very low therapeutic index of sulfide [58, 60, 89] and the incomplete understanding of endogenous sulfide metabolism during ischemia and after reperfusion

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Environ Sci Technol 6:529537 Vitvitsky V, Yadav PK, Kurthen A, Banerjee R (2015) Sulfide oxidation by a noncanonical pathway in red blood cells generates thiosulfate and polysulfides

Furthermore, previous reports documented that the aggregation of -synuclein is progressive for many years before the development of a symptomatic period (Chen et al

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