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In preclinical cancer models, COX-2 inhibition reduces tumor growth in COX-2-expressing tumors, and the pharmacodynamic readout is the reduction in tumor PGE2 concentration

56 LiJ.LiM.GeY.ChenJ.MaJ.WangC.et al (2022)

Long-acting muscarinic antagonists (LAMAs), such as tiotropium and aclidinium, reduce acetylcholine-mediated bronchoconstriction and suppress mucus hypersecretion by inhibiting goblet cell and submucosal gland activity [78, 79]

Avoid contamination by using sterile technique during each draw wipe the vial stopper with a 70% isopropyl swab and don't re-enter the vial with a needle that's been used elsewhere

134 , e174587 (2024)