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10.1016/j.jip.2019.107282 J

6 cycles at 21 day intervals

Even within individual clones from one patient, there is tremendous heterogeneity, such that numerous different gene expression profiles are expressed by the bacteria colonizing the lung, allowing for the selection of optimally fit clones 119, 120

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In contrast, VIP has anti-inflammatory effects, such as reducing the AHR and diminish of airway mucus secretion by the inhibition of ERK1/2 signaling pathway in murine models (Wang et al., 2018)