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The frequency of injections will depend on the individual

This product is a research material supplied strictly for laboratory research use only

Treatment doses typically range from 50 to 150 g daily of cyanocobalamin, preferably taken between meals, or 1,000 g daily for more rapid repletion, continued until deficiency is corrected

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As the insulin receptor is expressed in all cell types and insulin signaling mediates diverse cellular functions, the detailed insulin function of each tissue has been extensively studied using tissue-specific Insr knockout mice 3,5 , in which Insr expression is almost completely disrupted in a specific cell type