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Analyzed the 2.59 crystal structure of human SQOR and found that the enzyme is monomeric with a positively charged surface groove capable of binding receptor molecules such as sulfite and glutathione

10.3390/ijms26072959 121 MengQ.DuanX.-P.WangC.-Y.LiuZ.-H.SunP.-Y.HuoX.-K.et al (2017)

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Genetic and epigenetic factors Genetic predispositions significantly influence the risk of developing DPN