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Other assessments included changes in laboratory parameters (including but not limited to haematology and biochemistry), and physical examination, vital signs and ECG

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Intriguingly, Syn WT showed no detectable binding affinity towards the Syn WT -141C construct, indicating that monomeric Syn is functionally inert in solution (Fig

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While VAL2240 and ASP2195 are the important amino acids of the crystal structures of MTOR, particularly in the kinase domain (Fig