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We argue that viewing MS through the lens of an early onset, slowly progressive cytodegeneration of white and gray matter elements, convolved with a variable overlay of adaptive autoimmunity, could readily explain the entire disease spectrum, and aligns well with emerging new evidence

The study used pure enzyme system and thermal stabilization assays to arrive at this conclusion, which challenges the previously reported mechanism of RSL3 and ML162 inducing ferroptosis [199]

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A: These mechanisms can improve glucose control by enhancing glucose-dependent insulin secretion and reducing appetite and body weight