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Moreover, the deficiency of the endothelial glucocorticoid receptor was found to regulate EndMT via the Wnt/-catenin pathway in DKD [38]

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[DOI] [PubMed] [Google Scholar] Zhao J, Harada N, Kurihara H, Nakagata N, Okajima K

Insulin resistance (HOMA-IR) and body fat (%) are associated to low intake of fruit and vegetables in Swedish, young adults: the cross-sectional lifestyle, biomarkers and atherosclerosis study

The mechanisms through which progestins exert their therapeutic effects are the anti-estrogenic effects, anti-vasculogenic action, induction of apoptotic cascade in endometriotic cells, suppression of inflammatory pathways (as production of metalloproteinases), cell proliferation suppression, and also anti-neurogenic effects with inhibition of nerve growth within endometriotic lesions [59, 63, 64]